An Overview Of Rheumatoid Arthritis
What is Rheumatoid Arthritis?
Rheumatoid arthritis is a chronic inflammatory disease in which the lining of your joints becomes inflamed, causing pain, swelling, and stiffness. It is an autoimmune disease because it occurs when your immune system, which normally fights against infection, starts destroying healthy joints. Severe rheumatoid arthritis can be very painful and even cause deformity in a joint. It also affects your ability to perform routine activities.
Causes of Rheumatoid Arthritis
In rheumatoid arthritis, the immune system attacks the synovium, the membrane that lines the joints. Why this happens is unclear. It could be genetic or triggered by a bacterial or viral infection. The inflamed and thickened synovium damages the cartilage and bone as well as the other structures surrounding and supporting the joint. There is weakening of the tendons and ligaments and eventually, the joint becomes deformed and out of alignment.
Rheumatoid arthritis can affect anyone, but it occurs more often in women, between the ages of 40 to 60, those who are obese and smokers.
Symptoms of Rheumatoid Arthritis
- Swelling, warmth and tenderness at the joints
- Joint stiffness that is worse in the morning, or after periods of rest or inactivity
- Weight loss
The symptoms may vary in severity. They sometimes flare up or worsen, and at other times, are controlled (in remission). Joint deformity occurs at a later stage.
Rheumatoid arthritis may also affect other structures of the body such as the skin, eyes, salivary glands, lungs, heart, blood vessels, bone marrow, kidneys and nerves.
Complications Associated with Rheumatoid Arthritis
- Osteoporosis, both from rheumatoid arthritis as well as its treatment
- Infections due to an impaired immune system
- Heart problems due to inflammation of the surrounding membranes
- Lung disease due to inflammation and scarring of the lung tissue
- Carpal tunnel syndrome
- Tissue lumps or growths called rheumatoid nodules
- Increased body fat
- Blood cancers originating in the lymphatic system
Diagnosis of Rheumatoid Arthritis
Your doctor may order:
- Blood tests that detect inflammation in the body
- Imaging tests such as X-rays, ultrasound or MRI to view the joints and check the progress of the disease